AMP 5 Paste is an oral vasodilator from CEVA, made for horses and dogs to increase blood flow to cardiac and skeletal muscle during hard work. It contains adenosine-5-monophosphate (AMP-5) at 200 mg/mL, a naturally occurring nucleotide that widens blood vessels so more oxygen, nutrients and energy reach working muscle and the heart, while waste products such as lactic acid are cleared away more efficiently.
What is the active ingredient?
The active ingredient is adenosine-5-monophosphate (AMP-5) at 200 mg/mL, a naturally occurring nucleotide that acts as a vasodilator to increase blood flow to skeletal and cardiac muscle.
What is AMP 5 Paste used for?
AMP 5 Paste is used as a coronary and peripheral vasodilator, which in plain terms means it improves circulation to the muscles and heart. By boosting blood supply during intense effort, AMP-5 helps delay the onset of muscle fatigue and cramping and is valued in the treatment and prevention of tying up (exertional rhabdomyolysis). Because of its effect on cardiac muscle, AMP-5 is also used to help guard against heart strain and exercise-induced T-wave changes in horses. It is commonly given before racing, endurance work and other demanding activities. The manufacturer lists the product as available for general sale, so always follow the label and your veterinarian’s advice.
Key benefits and features:
- Increases circulation: raises blood, nutrient and energy supply to hard-working muscle tissue.
- Delays fatigue: improves removal of lactic acid and other wastes to help reduce cramping and tiredness.
- Supports the heart: may help prevent heart strain during and after strenuous exercise.
- Tying-up support: of value in the treatment and prevention of tying up.
- Pairs well: often combined with COpHOS B, Tripart and L-Carnitine in a race-preparation routine.
How to use AMP 5 Paste?
Dosing should always follow the product label and the direction of your veterinarian. The manufacturer’s general guidance is:
- Adult horse: 10 mL orally.
- Dogs: 1 mL per 10 kg bodyweight.
- Timing: give the first dose about 24 hours before, and again 4-6 hours before, expected strenuous exercise, or as directed by your veterinary surgeon.
- Administration: place the nozzle into the side of the mouth and deposit the paste as far back over the tongue as possible.
How does AMP 5 Paste improve performance and recovery?
Hard exercise creates a high demand for oxygen and fuel in muscle, plus a build-up of waste like lactic acid that triggers fatigue and cramp. The paste works by promoting vasodilation, the widening of blood vessels, so the cardiovascular system can deliver more oxygen and nutrients to muscle and the heart while clearing waste away faster. The result is muscle that keeps working efficiently for longer and recovers more comfortably afterwards.
When should it be given before a race?
The manufacturer suggests two doses for horses: one about 24 hours before and another 4-6 hours before expected strenuous exercise, or as directed by your veterinarian. Always check local racing rules and withdrawal requirements first.
How should it be stored?
Store below 30C at room temperature and protect from light, and keep out of reach of children. This product is for animal treatment only. Camel trainers who need an injectable route should note that AMP-5 is also available as an intramuscular injection. As with all performance products, observe local racing and anti-doping regulations and any required withdrawal times before competition.
Explore more options on our Horse & Camel Performance Supplements, or pair AMP 5 Paste with our CEVA L-Carnitine Injection for added energy support. For full manufacturer details, see the official CEVA AMP 5 Paste product page.


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